...Retinoic acid binds to all three kinds of retinoid receptors: alpha, beta, and gamma. It is thought that the gamma receptor is the most important in the pathogenesis of acne, and retinoic acid has a very high affinity for gamma receptors. First of all, there is sebum. Sebum itself might be comedogenic, but whether it is or not, it certainly provides the nutrient material for P acnes. The proliferation of this microorganism is the next pathogenic factor. ...»
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«...When you exercise, the internal organs tend to function in a better manner. It also improves your cardio-vascular fitness. The kidneys, bowel and liver start working well....»
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